General Medicine is a foundational course for medicine courses that emphasizes on the diagnosis, treatment, and management of prevalent systemic diseases in animals. It deals with General systemic states: toxemia, septicemia, bacteremia, fever, hyperthermia, hypothermia, heat stroke, dehydration, electrolytes and acid-base imbalances, allergies. Diseases of alimentary system: stomatitis, pharyngitis, esophageal disorders, simple indigestion, ruminal acidosis and alkalosis, ruminal tympany, traumatic reticuloperitonitis/ pericarditis, impaction of abomasum, neonatal infections, enteritis, equine colic, gastritis and principle of GIT treatment. Hepatobiliary System, Hepatitis, jaundice and cholelithiasis. Cardiovascular system: arrhythmias, myocarditis, endocarditis, valvular heart disease, circulatory failure, thrombosis and embolism, congenital cardiac defects and shock, edema. Hematopoietic and hemolymphatic system: anemia, leukemia, leucopenia. Respiratory system: pneumonia, bronchitis and pleurisy. Diseases of the urinary, nervous and musculoskeletal systems.